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Topsy and Tim's Little ABC Library

Формат:      Страниц 60
     мягкая обложка
Автор:
Jean A.    
Издательство:
Ladybird Books    
Год:2009
Цена:
220 руб
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With colourful, bold images and clear words preschool children will love learning their alphabet with Topsy and Tim. This title includes six brightly coloured mini books featuring Topsy and Tim, contained in a little case. For example, the letter ' c' , the word ' cat' and a picture of a cat. Topsy & Tim remain instantly recognisable to parents while in a fresh style that will appeal to a new generation of fans, these wonderful books deserve a place on every child' s bookshelves. The set runs through the whole alphabet, introducing each letter, a word and a simple image on the opposite page. A trusted and well-loved pair who can help guide parents and children through ' first experiences' , Topsy and Tim books have been beautifully updated with contemporary artwork.
Как мы встречали Новый год. Видео-открытка (+ DVD).
Уникальные кадры кино-хроники 30-90 гг. ХХ века. Документальный проект «Как мы встречали новый год!» предлагает вашему вниманию уникальные
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Раздел: Открытки к Новому году и Рождеству
Конструктор "Архитектурное моделирование. Полиция", 270 деталей.
Строительный набор для творчества "Архитектурное моделирование" содержит все, что необходимо для создания макета сооружения. А
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Раздел: Поделки по созданию предметов из пластика, полимеров, стекла
Кружка "Лучшая Подруга в мире", с рисунком.
Качественные керамические кружки с оригинальным рисунком, выполненным в процессе производства (подглазурное нанесение). Упаковка: белый
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Раздел: Кружки

Бактериальная система секреции белков первого типа
Целью данной работы является сбор и обобщение имеющейся на этот день информации о бактериальной системе секреции первого типа. Краткая характеристика бактериальных систем секреции Для секреции белков бактериальные клетки используют различные системы секреции в зависимости от строения и конечной локализации белка. Поэтому является необходимым приведение небольшого обзора систем секреции всех типов. Секреция первого типа. Аппарат этой системы секреции устроен относительно просто. Он включает в себя три компонента белковой природы. Эта система является Sec-независимой и осуществляет секрецию субстратов непосредственно из цитоплазмы в одну стадию без периплазматических посредников. По этому пути секретируются токсины, протеазы, липазы, антибиотики и другие соединения (D. ha assi e al., 2000). Секреция второго типа. Эта система секреции устроена уже довольно сложно. Характерной особенностью является ее разделение на две части и секреция субстратов в две стадии. Первая часть, называемая Sec-системой, экспортирует белки через цитоплазматическую мембрану, далее белки либо остаются в периплазме, либо секретируются через внешнюю мембрану посредством терминальных компонентов системы секреции (S. Lory, 1998). По этому пути секретируются такие белки, как пектатлиазы, пектинметилэстеразы и целлюлазы рода Erwi ia, целлюлаза, протеаза и амилаза Xa homo as campes ris, липаза, фосфолипаза, эластаза, энтеротоксин А у Pseudomo as aerugi osa, амилаза и протеаза Aeromo as hydrophila, хитиназа, протеаза и холерный токсин Vibrio cholerae (J. Hacker a al., 2000). В связи с большим количеством и разнообразием субстратов, секретируемых через этот аппарат секреции, его называют белка, формирующего периплазматический канал, соединяющий ABC-транспортер с третьим компонентом системы – белком-швейцаром, образующим секреторный канал во внешней мембране.


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