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INTERACTIONS OF FLAVONES AND RELATED COMPOUNDS WITH NUCLEIC ACIDS. An approach to study interactions between natural compounds with nucleic acids and synthesis of flavonoid derivatives

Формат:      Страниц 260
     мягкая обложка
Patricia R.A.    
Книга по Требованию    
3191 руб
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Interactions between with genomic DNA, synthetic polynucleotides and higher order DNA isoforms (triple and quadruple helical forms) have been studied. The process of identification of the active compounds and their synthesis, optimisation and development for new drug candidates appropriate for clinical use is described as Medicinal Chemistry; a discipline merging chemistry and pharmacology. This book provides information and protocols for studying drug-DNA interactions using spectroscopical and biological techniques; synthesis of flavonoids and the principles to explore the use of Quantitative Structure Activity Relationship Studies. This monograph describes a group of active ingredients from herbal medicines, as a foundation for the development of new anticancer drugs. Across the world, different diseases have been treated with herbal extracts, based on common and empiric knowledge. Rational drug design has been also employed during this project to elucidate the mode of binding and novel compounds have been synthesized to provide precise structure-activity related studies resulting in a second generation of chemotherapeutic anticancer agents with improved properties.
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Количество переносов в данном монологе составляет 7 случаев. Кроме того, нами отмечены 3 случая элизии he le ers, ha h give , o he и в случая редуцированных форм слов: li k'd и o' h'. Душевное волнение, жажда битвы накладывают свой отпечаток на речь и она становится синтаксически менее правильной. Рассмотрим другой монолог, посвященный той же теме: Hear me, quee : he s ro g ecessi y of ime comma ds Our services awhile; bu my full hear Remai s i use wi h you. Our I aly Shi es o'er wi h civil swords: Sex us Pompeius Makes his approaches o he por of Rome; Equali y of wo domes ic powers Breed scrupulous fac io ; he ha ed, grow o s re g h, Are ewly grow o love. he co dem 'd Pompey, Rich i his fa her's ho our, creeps apace I o he hear s of such as have o hrived Upo he prese s a e, whose umbers hrea e ; A d quie ess, grow sick of res , would purge By a y despera e cha ge. My more par icular, A d ha which mos wi h you should safe my goi g, Is Fulvia's dea h. Здесь мы видим совершенно другую ситуацию: Антоний убеждает Клеопатру в необходимости своего отъезда, он строит свою речь синтаксически правильно, хотя ритмика и достаточно большое отклонение от иктовых позиций говорят о душевном волнении и нерешительности.

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Молочный гриб можно использовать для похудения, восстановления микрофлоры, очищения организмаМолочный гриб можно использовать для похудения, восстановления микрофлоры, очищения организма

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