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Molecular Dissection of the Clonal M1T1 Group A Streptococci. Integrating Genomics, Proteomics, and Bioinformatics Tools to Define the Unique Features of a Pandemic Flesh-Eating Bacterial Strain

Формат:      Страниц 164
     мягкая обложка
Автор:
Ramy K.A.    
Издательство:
Книга по Требованию    
Год:2009
Цена:
2769 руб
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A particular strain of the group A streptococci (GAS), known as the M1T1 clone, has exhibited unusual epidemiology and virulence, and has been largely associated with the pandemic of invasive GAS infections worldwide. This book, based on my PhD dissertation, discusses unique features that may have endowed the global M1T1 clone with its unusual properties, and the genomic and evolutionary basis for its emergence and persistence. Among M1T1' s unique features are its ability to switch to a hypervirulent phenotype with a survival advantage in deep tissues; the acquisition and exchange of mosaic prophages that encode novel exotoxins; and the production of the potent DNase Sda1, which frees the bacteria from the leukocyte extracellular traps. The resurgence of the severe diseases was thus suspected to be a result of an unusual pathogenic potential inherent to the few reemerging strains. M1T1 was among few GAS strains that have outnumbered other serotypes since the mid-1980s, and their increase in GAS populations coincided with the resurgence of invasive and severe forms of streptococcal diseases, especially the streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis (NF).
Настольная игра "Барабашка (Geistestesblitz)".
У вас в руках оказались фотокарточки, сделанные каким-то странным фотоаппаратом: фотографируя всего пять предметов, он постоянно путает их
1071 руб
Раздел: Внимание, память, логика
Бумага туалетная "Classic (Вейро)", 24 рулона, 17 метров x 9.5 см.
В комплекте: 24 рулона. Длина рулона: 17 метров. Ширина рулона: 9,5 см. С перфорацией. В одном рулоне: 136 листов.
396 руб
Раздел: Бумага туалетная
Рюкзак для средней школы "Райдер", 46x34x18 см.
Рюкзак для средней школы. 2 основных отделения, 4 дополнительных кармана. Формоустойчивая спинка. Ремни регулировки объема. Материал:
978 руб
Раздел: Без наполнения

Страховой рынок в России и за рубежом
В 1996 году совет директоров утвердил основные положения концепции развития группы Ингосстраха на долгосрочную пятилетнюю перспективу, цель которой - войти в число ведущих мировых страховых компаний и стать крупным инвестором в национальную экономику. В настоящее время туристы, выезжающие за рубеж и являющиеся полисодержателями Ингосстраха, имеют возможность пользоваться круглосуточной диспетчерской службой и неотложной медицинской помощью компании IM Assis e s. Эта компания является дочерним предприятием Ингосстраха. Поэтому полис по добровольному медицинскому страхованию действует в любом городе РФ и во всех государствах СНГ. Ингосстрах предлагает новые страховые продукты, например программу «Плановая и экстренная госпитализация с проведением сложных операций за рубежом». Ингосстрах представляет РФ в крупнейшей международной сети IGP (I er a io al Group Program), объединяющей боле сорока ведущих национальных страховых компаний и более 500 крупнейших транснациональных корпораций. Направление работы сети – страхование жизни персонала компании. Целью IGP является обеспечение для членов сети единого уровня страховых услуг во всех странах, где её участники ведут бизнес.


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Молочный гриб можно использовать для похудения, восстановления микрофлоры, очищения организмаМолочный гриб можно использовать для похудения, восстановления микрофлоры, очищения организма

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