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Molecular Dissection of the Clonal M1T1 Group A Streptococci. Integrating Genomics, Proteomics, and Bioinformatics Tools to Define the Unique Features of a Pandemic Flesh-Eating Bacterial Strain

Формат:      Страниц 164
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Ramy K.A.    
Книга по Требованию    
2769 руб
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A particular strain of the group A streptococci (GAS), known as the M1T1 clone, has exhibited unusual epidemiology and virulence, and has been largely associated with the pandemic of invasive GAS infections worldwide. This book, based on my PhD dissertation, discusses unique features that may have endowed the global M1T1 clone with its unusual properties, and the genomic and evolutionary basis for its emergence and persistence. Among M1T1' s unique features are its ability to switch to a hypervirulent phenotype with a survival advantage in deep tissues; the acquisition and exchange of mosaic prophages that encode novel exotoxins; and the production of the potent DNase Sda1, which frees the bacteria from the leukocyte extracellular traps. The resurgence of the severe diseases was thus suspected to be a result of an unusual pathogenic potential inherent to the few reemerging strains. M1T1 was among few GAS strains that have outnumbered other serotypes since the mid-1980s, and their increase in GAS populations coincided with the resurgence of invasive and severe forms of streptococcal diseases, especially the streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis (NF).
Настольная игра "Барабашка (Geistestesblitz)".
У вас в руках оказались фотокарточки, сделанные каким-то странным фотоаппаратом: фотографируя всего пять предметов, он постоянно путает их
1071 руб
Раздел: Внимание, память, логика
Бумага туалетная "Classic (Вейро)", 24 рулона, 17 метров x 9.5 см.
В комплекте: 24 рулона. Длина рулона: 17 метров. Ширина рулона: 9,5 см. С перфорацией. В одном рулоне: 136 листов.
396 руб
Раздел: Бумага туалетная
Рюкзак для средней школы "Райдер", 46x34x18 см.
Рюкзак для средней школы. 2 основных отделения, 4 дополнительных кармана. Формоустойчивая спинка. Ремни регулировки объема. Материал:
978 руб
Раздел: Без наполнения

Страховой рынок в России и за рубежом
В 1996 году совет директоров утвердил основные положения концепции развития группы Ингосстраха на долгосрочную пятилетнюю перспективу, цель которой - войти в число ведущих мировых страховых компаний и стать крупным инвестором в национальную экономику. В настоящее время туристы, выезжающие за рубеж и являющиеся полисодержателями Ингосстраха, имеют возможность пользоваться круглосуточной диспетчерской службой и неотложной медицинской помощью компании IM Assis e s. Эта компания является дочерним предприятием Ингосстраха. Поэтому полис по добровольному медицинскому страхованию действует в любом городе РФ и во всех государствах СНГ. Ингосстрах предлагает новые страховые продукты, например программу «Плановая и экстренная госпитализация с проведением сложных операций за рубежом». Ингосстрах представляет РФ в крупнейшей международной сети IGP (I er a io al Group Program), объединяющей боле сорока ведущих национальных страховых компаний и более 500 крупнейших транснациональных корпораций. Направление работы сети – страхование жизни персонала компании. Целью IGP является обеспечение для членов сети единого уровня страховых услуг во всех странах, где её участники ведут бизнес.

Analysis of the Co-existing Group I and Group II Chaperonins in M. mazei Protein Folding in Archaea. Книга по Требованию
In addition, the unique coexistence of both chaperonin groups in M. mazei allowed direct comparison of the substrate spectra of a bacterial and a eukaryo-typic folding machine.
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It is found out that some meaningful and relevant theological implications could be derived from a wider focus on the song as a whole artistic production and not from a mere isolation of lyrics for critical literary analysis.
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This scholarly yet engaging text will appeal to those readers who appreciate the nuances of narrative voice and have an interest in the literary representation of women' s inner experience. The techniques of both internal and narrated monologue and communal narration are explained and rigorously examined with reference to the work of eminent narratologists and literary theorists, including Julia Kristeva, Mikhail Bakhtin, Dorrit Cohn and Susan Sniader Lanser. Here, through an exploration of narrative voice in two contemporary literary novels - Marie Darrieussecq' s ' A brief stay with the living' , and her own work, ' Dissection' - Jacinta Halloran makes a compelling argument for the privileging of some narrative styles over others in the literary representation of women' s inner lives. If language is a patriarchal construct, what is it to write of a woman' s consciousness?
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The Measurement Of Groups And Series A Course Of Lectures Книга по Требованию Bowley A.L.
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The Best of Newspaper Design: 29 Rockport Publishers The S.f.N.D.
Every industry professional aspires to one day see his or her work in this book.
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The life and revelations of Saint Gertrude, virgin and abbess, of the Order of St. Benedict Книга по Требованию Gertrude t.g.
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The Best of News Design: 32 Rockport Publishers The S.f.N.D.
Every industry professional aspires to one day see his or her work in this book.
2121 руб
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Most industrial countries today are facing serious problems regarding old age security.
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Structural characterisation of NSAIDS and cyclodextrin-NSAID complexes. A study at the molecular level Книга по Требованию Pamela M.D.
These different species, due to their different crystal structures have different physical properties such as solubility and dissolution rate and therefore the most appropriate polymorph needs to be identified for optimum bioavailability.
2403 руб
Functional Renormalization Group for Interacting Bosons. Application to the symmetry broken phase Книга по Требованию Andreas S.
The physics of interacting bosons in the phase with broken symmetry is very different from the physics in the symmetric phase.
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Voices of the Volunteers. An Exploration of the Influences that Volunteer Experiences Have on the Resilience and Sustainability of Catchment Groups in Coastal Queensland Книга по Требованию
Analysis of these conceptions enhanced an understanding of how resilience may be developed in community-based stewardship groups.
3234 руб
Establishment of Molecular Genetic Methods for the Analysis of Ibex Faeces The Potential of Non-invasive Samples for Genetic Studies. Книга по Требованию
The author, Kristina Salzer, gives an overview of the potential for and limitations of non-invasive sampling approaches.
2008 руб
Participants were asked to locate or detect a different region or element in multi-element displays.
2784 руб
Homotopy Theory of Modules. Absolute and Relative Homotopy Groups of Modules using the Injective Homotopy Category Книга по Требованию Beatrice B.
A discussion of the categorical notion of duality precedes the definition of the injective homotopy category.
2008 руб
Do vitamins C and E affect respiratory infections?. Vitamin supplementation does not affect the incidence of respiratory infections in ordinary people but may affect restricted population groups Книга по Требованию Harri H.
Regular vitamin C supplementation shortens the duration of common cold infections.
2416 руб
Group Meeting Behavior. The Effective of Work Group Climate Книга по Требованию Chin-Shih T.
This book presents the results of study investigating relationships between work group climates and meeting behaviors, as perceived by group members.
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What happens when groups say sorry?. The effects of intergroup apologies for their recipients Книга по Требованию Catherine P.
Surveys assessing awareness of Japan' s apologies for World War II were conducted in Australia, the Philippines and Malaysia. A series of laboratory experiments were also conducted to establish if significant differences in forgiveness arise after the delivery of an apology. Taken together, the results give a measured view of the usefulness of intergroup apologies in promoting intergroup forgiveness. This research represents an attempt to answer this question. Intergroup apologies have been provided as reparation for all manner of offences from genocidal massacres to prejudicial government policies. Yet, for each circumstance in which apologies are offered, there are others in which apologies are not given though victim groups demand them. Yet, little is known of the actual effectiveness of intergroup apologies for victim groups. The frequency of intergroup apologies and requests suggests that these are important and not without cost.
3234 руб

Молочный гриб можно использовать для похудения, восстановления микрофлоры, очищения организмаМолочный гриб можно использовать для похудения, восстановления микрофлоры, очищения организма

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