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Inference of regulatory interactions in genetic systems. Optimization-based techniques using microarray data

Формат:      Страниц 168
     мягкая обложка
Автор:
Reuben T.    
Издательство:
Книга по Требованию    
Год:2009
Цена:
2784 руб
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The techniques proposed have advantages over the current methods used in that they not only capture the inherent non-linearity of the process but also account for the regulatory behavior of proteins and handle data directly from DNA microarray experiments. They are designed to handle data arising from experimental setups like DNA microarrays. The data used were steady state data from the set of genes involved in the SOS response of E. Coli and time-varying data from a subset of genes involved in the formation of the endospore in the Bacillus anthracis. The main focus of this thesis is the development of techniques to aid in the process of inferring how genes interact with each other in a living organism. They were validated using both simulated data and also data from real organisms. Knowledge of these interactions have implications in gaining an understanding of how cellular processes work, how organisms survive and evolve under different environmental conditions. The techniques are based on an S-system type differential equation model for the process of gene regulation. Methods to handle data collected under both steady state and time-varying manner are developed.
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Изучение возможности применения магнитных жидкостей для синтеза магнитных...
Министерство народного образования Республики Беларусь Беларусский ордена трудового красного знамени государственный университет имени В.И. Ленина Химический факультет Кафедра неорганической химии Изучение возможности применения магнитных жидкостей для синтеза магнитных сорбентов Дипломная работа студентки 5-го курса Кекало Екатерины Александровны Руководитель канд. хим. наук, доцент Н.Н. Горошко Рецензент доктор хим. наук, профессор Е.А. Стрельцов Дипломник Е.А. Кекало ласцiвасцей. his work devo es o s udy he possibili y of use he ferrofluids for mag e ic sorbe s sy heses. I he prese work ew me hods of recep io of he mag e ic sorbe s, based o use of various mag e ic liquids are submi ed Use of a liquid ma erial for impreg a io of a sorbe (a d givi g o i hus mag e ic proper ies) favourably dis i guishes he way offered by us from described i he li era ure. Applica io of various mag e ic liquids (as agai s mag e i e he cer ai s ruc ure) allows o vary proper ies of a received sorbe over a wide ra ge. Researches have show , ha a mag e iza io of a sorbe by mea s of mag e ic liquids i s specific surface decreases a li le bi . hus, he sorbe ge s valuable mag e ic proper ies o losi g he i dividual proper ies. . Приложение Рис.24 Результат термического анализа активированного угля Потери массы, % Температура, єС Рис.25 Результат термического анализа активированного угля с магнетитом Потери массы, % Температура, єС Рис.26 Результат термического анализа активированного угля, пропитанного МЖ (водн, олеат ТЭА) Потери массы, % Температура, єС


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