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Phytochemical Investigation and Pharmacological Screening. Phytochemical Investigation, Characterization and Pharmacological Screening of Butea Frondosa

Формат:      Страниц 84
     мягкая обложка
Dharmendra K.    
Книга по Требованию    
1894 руб
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Chloroform and Methanol (9: 1) were used as eluent for separation of desired compound from the crude extract. In Chromatographic studies the TLC plates were observed using different solvent systems, detected under short wave UV spectrophotometer, with a Rf value of 0. 26, 0. 30, 0. 42, 0. 55. After conducting phytochemical test, focus was on to isolate the desired compound using repeated column chromatography. In view of the literature findings, sufficient studies were reported on flowers and seeds, and lesser attention was paid towards leaves. Therefore, the present study was planned to concentrate upon leaves and was selected for the study, which is a rich source of phytoconstituents. The present study was undertaken with the objective to explore the anticataract potential of methanolic extract of Butea frondosa leaves by oxidative stress (Hydrogen peroxide) in Goat eyes (lens) and also the anti-inflammatory activity of aqueous extract of Butea frondosa bark in rats. Butea frondosa is commonly known as Palash and the plant belongs to family Leguminosae.
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For he firs ime here was revealed a high a iaggrega io ac ivi y of melilo ex rac (i vi ro) a d es ablished i s marked hypocoagula io proper ies i he effec o coagula io hemos asis of he experime al a imals. I was fou d ha ex rac of melilo ac iva ed he fibri oly ic sys em: i promo ed reduc io of fibri oge providi g ormaliza io of rheology a d blood microcircula io . I modeli g hyphema i rabbi s i was ascer ai ed ha applica io ex rac of melilo i creased fibri oly ic po e ial of he lacrimal fluid by ormaliza io of i s coagula io ac ivi y ha co siderably reduced he period of hemorrhage resorp io . he same herapeu ic efficacy ex rac of melilo was de ermi ed i depe da of he me hod of applica io : subco ju c ively or subcu a eously. Special pharmacological es s for bios imula ors made of a ural raw ma erials revealed a high level of biological ac ivi y ex rac of melilo , a i oxic a d a ihypoxia effec . Accordi g o he da a of elec ro ic-microscopic me hods of i ves iga io of he hepa ic cells i was es ablished ha ex rac of melilo i creased resis a ce of hepa ocy es by mea s of ac iva io of pro ei -sy hesis a d e ergy- formi g fu c io .

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